Gene: [12q131/HNRPA1] heterogeneous nuclear ribonucleoprotein A1 (34 kD); RNP particle, heterogeneous nuclear, A1 protein (34 kD);
MOP | A1 protein isoforms were found. They differ in single amino acid substitutions and 3'-UTR length (two mRNA species - 1.5 and 1.9 kb) due to alternative polyadenilation sites." |
FAG | Several polypeptides associated with the fraction of hnRNA (primary transcripts of RNA polymerase II) within the nuclear RNP particles, including (besides A1 protein) A2/B1 (36kD/37kD; GEM:07p15/HNRPA2B1), B2 (38kD), C1/C2 (41kD/43kD; GEM:00.0/HNRPC), as well as proteins G (GEM:06p12/HNRPG), L (GEM:00.0/HNRPL), and the product of A1-like gene (GEM:01p32/HNRPA1L). According to Buvoli-1988, the total number of components of this multigene family may reach 30. They are supposed to code for about 20 different proteins, their MM varying from 34kD to 120kD, which are constituents of nuclear RNP particles." |
REF | CLO,SEQ,STR,EXP "Biamonti G &: J Mol Biol, 207,
491-503, 1989 PRO,COD,SEQ,EXP,FAG,EVO "Buvoli M &: NAR, 16, N9, 3751-3770, 1988 LOC "Saccone S &: Genomics, 12, N1, 171-174, 1992 |
SWI | SWISSPROT: P09651 |
KEY | trc |
CLA | coding, basic |
LOC | 12 q13.1 |
MIM | MIM: 164017 |
