Gene: [12q1/LIPO] lipomatosis, multiple, familial; breakpoint associated with benign lipoma; [BABL ]

COM

 The gene BABL has been excluded from the GDB. The MIM registered it as LIPO (lipomatosis, multiple). It is mapped by cytogenetic methods, on the basis of pathology manifestation in carriers of translocations involving segments q13-14 of Chr 12."

HET

 [1] According to Heim-1988 and Mandahl-1988, multiple lipomatosis represents a heterogeneous group of benign adipose tissue tumors and includes at least three clinical cytogenetic variants.
[2] The locus for myxoid liposarcoma is identified: GEM:12q13/DDIT3."

REF

 LOC,CYG "Dal Cin &: Cancer Genet Cytogenet, 31, 237-240, 1988
LOC,CYG "Dal Cin &: CCG, 46, (HGM9), 602-603, 1987
LOC,CYG "Heim S &: Int J Cancer, 42, 863-867, 1988
HIS,PAT,FOG "Kurzweg, Spencer: Am J Surg, 82, 762-765, 1951
LOC,CYG "Mandahl N &: Hum Genet, 79, 203-208, 1988
LOC,CYG "Mandahl N &: Int J Cancer, 39, 685-688, 1987
HIS,PAT,FOG "Rabbiosi &: Acta Derm Venerol, 57, 265-267, 1977
HIS,PAT,FOG "Shanks &: Can Med Assoc J, 77, 881-884, 1957
HIS,PAT,FOG "Stephens, Isaacson: J Hered, 50, 51-53, 1959
HIS,PAT,FOG "Weinberg &: Am J Med Genet, 5, 57-67, 1980

KEY

 onc, lip, chr

CLA

 unknown, basic

LOC

 12 q13-14

MIM

 MIM: 151900

SYN

 BABL