Gene: [12q242/OAS2] 2'-5'oligoadenylate synthetase 2;

COM

The OAS2 gene was mapped to Chr 12q24.2 by fluorescence in situ hybridization and by inclusion within mapped clones (Hovnanian-1998)."

FUN

The 2-prime,5-prime oligoadenylate synthetases catalyze the synthesis of 2-prime,5-prime oligomers of adenosine (2-5As)."

REF

CLO,EXP "Hovanessian AG &: EMBO J, 6, 1273-1280, 1987
LOC,FAG "Hovnanian A &: Genomics, 52, 267-277, 1998
EXP,FUN "Marie I &: Eur J Biochem, 248, N2, 558-566, 1997
COD,SEQ,EVO "Marie I, Hovanessian AG: JBC, 267, 9933-9939, 1992
EXP,FUN "Marie I &: BBRC, 160, 580-587, 1989
EXP,FAG "Witt PL &: J Interferon Res, 13, N1, 17-23, 1993

SWI

SWISSPROT: P29728

KEY

nucm

CLA

coding, basic

LOC

12 q24.2

MIM

MIM: 603350

EZN

ENZYME: 2.7.7.19

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