Gene: [12q243/RSN] restin (Reed-Steinberg cell expressed intermediate filament-associated protein); Hodgkin disease, associated protein;

COM

Restin is an intermediate filament-associated protein, the expression of which is limited to Reed-Sternberg cells, characteristic of Hodgkin disease, and in vitro cultivated peripheral blood monocytes (Bilbe-1992; Delabie-1992)."

REF

EXP,MOP "Bilbe G &: EMBO J, 11, 2103-2113, 1992
EXP,MOP "Delabie J &: Blood, 80, 2891-2896, 1992
LOC "Hilliker C &: CCG, 65, 172-176, 1994

SWI

 SWISSPROT: P30622

KEY

imm, onc

CLA

coding, basic

LOC

12 q24.3

MIM

 MIM: 179838