Gene: [12q2/PMCH] pro-melanin-concentrating hormone;

FAG

Pedeutour-1994 mapped the PMCH gene to Chr 12q23-q24 and identified 2 PMCH-like genes on Chr 5 (GEM:05p14/PMCHL1 and GEM:05q1/PMCHL2) by in situ hybridization."

EXP

The PMCH precursor encodes 3 neuropeptides: MCH, NEI and NGE.

REF

LOC "Nahon JL &: Genomics, 12, 846-848, 1992
LOC "Pedeutour F &: Genomics, 19, 31-37, 1994
IDN "Presse F &: Mol Endocrinol, 4, 632-637, 1990
FUN "Qu D &: Nature, 380, N6571, 243-247, 1996

SWI

 SWISSPROT: P20382

KEY

derm, horm

CLA

coding, basic

LOC

12 q23-24

MIM

 MIM: 176795