Gene: [13q1411/CPB2] carboxypeptidase B2 (plasma); arginine carboxypeptidase (kininase 1); carboxypeptidase U; episodic angioedema (carboxypeptidase N? deficiency);

COM

Tsai-1992 assigned the CPB2 gene to Chr 13. Vanhoff-1997 refined the location to Chr 13q14.11 by fluorescence in situ hybridization."

FUN

[1] Systematic name: peptidyl-L-arginine hydrolase.
[2] The catalyzed reaction: peptidyl-L-lysine(or L-arginine) + H(2)O = peptide + L-lysine(or L-arginine)."

REF

IDN "Eaton DL &: JBC, 266, 21833-21838, 1991
CLO,SEQ "Gebhard W &: Eur J Biochem, 178, 603-607, 1989
CLO,LOC "Tsai SP, Drayna D: Genomics, 14, N2, 549-550, 1992
CLO,LOC "Vanhoof G &: Genomics, 38, N3, 454-455, 1996

SWI

SWISSPROT: P15169

KEY

hem, serp, pep

CLA

coding, basic

LOC

13 q14.11

MIM

MIM: 212070

EZN

ENZYME: 3.4.17.3

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