Gene: [13q/HTR2A] 5-hydroxytryptamine (serotonin) receptor 2A; schizophrenia, associated to HTR2A; [HTR2 ]

GEN

The gene length: 20 kb (approx.); exons: 3 (Chen-1992).

ASS

A metaanalysis suggests that the gene for 5-HT2a-receptor, or a locus in linkage disequilibrium with it, confers susceptibility to schizophrenia (Williams-1997)."

REF

GEN,SEQ "Chen K &: Brain Res Mol Brain Res, 14, 20-26, 1992
PRO,LOC,EAG,HUM,MOU "Hsieh CL &: Somat Cell Mol Genet, 16, 567-574, 1990
PRO,LOC,EAG,HUM,MOU "Sparkes RS &: Genomics, 9, 461-465, 1991
MUT,POL,PAT,ASS "Williams J &: Lancet, 347, N9011, 1294-1296, 1996

SWI

SWISSPROT: P28223

KEY

neu, recp, sign

CLA

coding, basic

LOC

13 q14-21

MIM

MIM: 182135

SYN

HTR2

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