Gene: [16q22/AML2] oncogene AML2?; acute myeloid leukemia 2;

COM

A linkage of AML2 locus with the microsatellite marker D16S522 (a maximum 2-point lod score of 2.82) at recombination fraction theta = 0.0, providing evidence for mapping to 16q22. Haplotype analysis showed a 23.5-cM region of 16q22 that was inherited in common by all affected family members and extended from D16S451 to D16S289 (Horwitz-1997)."

REF

PAT,LIN,LOC "Horwitz M &: AJHG, 61, 873-881, 1997

KEY

onc, hem

CLA

unknown, basic

LOC

16 q22

MIM

MIM: 602439

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