Gene: [17q2/FKHL13] forkhead (Drosophila)-like 13; [HFH-4 ]

COM

FKHL13 is the human homologue of the mouse hepatocyte nuclear factor 3/fork head homologue 4 (HFH-4) gene, a member of the HNF-3/fork head (also called winged helix) gene family. Members of this gene family contain a conserved DNA binding region of approx. 110 amino acids and are thought to play an important role in cell-specific differentiation (Murphy-1997)."

FUN

FKHL13 expression pattern suggests that the gene plays an important role in the differentiation of lung and oviduct/ ampulla epithelial cells and testicular spermatids (Murphy-1997)."

GEN

The gene length: 6 kb (approx.); exons: 2; introns: 1 (Murphy-1997).

REF

CLO,SEQ,LOC "Murphy DB &: Genomics, 40, N3, 462-469, 1997

KEY

onc, trc, ont

CLA

coding, basic

LOC

17 q22-25

MIM

MIM: 602291

SYN

HFH-4

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