Gene: [19q132/CYP2B6] cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6;

FAG

CYPABF gene cluster is located in chromosomal segment 19q132: FAM:CYP2ABF/19q132. On other genes of CYP2 subfamily, see FAM:CYP2/00.0. The total list of mapped CYP superfamily genes is presented in FAM:CYP/00.0. The basic bibliography is also given there."

PRO

Gene-specific DNA probe lambdaMP1 is a 1.855 kb fragment cloned at EcoRI site in the vector gt11 (Miles-1988)."

POL

Enzyme Alleles in kb/(Popul Frequencies) Const Bands in kb (Reference; Probe number)
[1] BamHI A1= 18.7/(0.59); A2= 9.4/(0.41) CB= 7.4 (Miles-1988; Probe 1)
[2] MspI B1= 2.9/(0.55); B2= abs (0.45) CBs=3.5+2.2+1.0 (Miles-1988; Probe 1)"

REL

EVO,FUN: FAM:CYP/00.0

REF

GEN,TRC,EXP "Miles JS &: NAR, 18, N1, 189, 1990
LIN,MAP "Miles JS &: NAR, 17, 2907-2917, 1989
CLO,SEQ,EXP,LOC,MOL,POL "Miles JS &: NAR, 16, N13, 5783-5795, 1988
LIN,MAP "Mitchell &: CCG, 51, (HGM10), 1045, 1989
LOC,CYG,MOL "Santisteban &: Ann Hum Genet, 52, 129-135, 1988
CLO,EXP,LOC,FAG "Yamano S &: Biochemistry, 28, N18, 7340-7348, 1989

KEY

xen

CLA

coding, basic

LOC

19 q13.2

MIM

MIM: 123930

EZN

ENZYME: 1.14.14.1

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