Gene: [22q112/MIF] macrophage migration inhibitory factor; glycosylation-inhibiting factor; phenylpyruvate tautomerase;
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FUN |
A macrophage migration inhibitory factor, originally described as a product of activated lymphocytes, was identified as a phenylpyruvate tautomerase (Resengren-1997, Suzuki-1997). It has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation." |
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REF |
CLO,SEQ,STR "Bernhagen J &: Biochemistry, 33, N47, 14144-14155, 1994 CLO,SEQ,STR,HET,LOC,MOU "Bozza M &: Genomics, 27, N3, 412-419, 1995 FUN "Bucala R: FASEB J, 10, N14, 1607-1613, 1996 LOC "Budarf M &: Genomics, 39, N2, 235-236, 1997 LOC "Kozak CA &: Genomics, 27, N3, 405-411, 1995 CLO,SEQ "Mikayama T &: PNAS, 90, 10056-10060, 1993 CLO,SEQ "Paralkar V, Wistow GJ: Genomics, 19, 48-51, 1994 FUN "Rosengren E &: FEBS Lett, 417, N1, 85-88, 1997 FUN "Suzuki M &: J Biochem, 122, N5, 1040-1045, 1997 CLO,SEQ "Weiser WY &: PNAS, 86, 7522-7526, 1989 CLO,SEQ,EXP "Wistow GJ &: PNAS, 90, N4, 1272-1275, 1993 |
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KEY |
cyk |
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CLA |
coding, basic |
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LOC |
22 q11.2 |
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MIM |
MIM: 153620 |
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EZN |
ENZYME: 5.3.2.1 |
