Gene family: ATP synthases [H+] transporting, mitochondrial; (ATP5A1 ATP5A2 ATP5AL1 ATP5AL2 ATP5B ATP5BL1 ATP5BL2 ATP5C ATP5CL1 ATP5CL2 ATP5D ATP5E ATP5O ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5GP1 ATP5H ATP5I ATP5J ATP5K)
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SUM |
[1] The mitochondrial F1F0-ATP synthase uses energy derived from a proton
gradient to synthesize ATP. The structure of this complex has been
referred to as a 'lollipop,' as the soluble F1 catalytic unit is
attached to the mitochondrial inner membrane via the F0 unit, which is
anchored in the membrane and connected via a stalk structure to the F1
unit.
[2] The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. Three proteins, designated e, f, and g, copurify with the F1F0 subunits, but are peripherally associated with the membrane or the stalk. The functions of these proteins are unknown." |
