Gene: [CSN/04q211] caseins; (CSN1 CSN2 CSN10)
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SUM |
The human caseins include alpha-S1-casein (GEM:04q211/CSN1) and beta-casein (GEM:04q211/CSN2), which are the substrates for protein kinase (see GEM:13q13/CSNK1A1 and GEM:20p13/CSNK2A1) and precipitate in the presence of calcium (so called calcium-sensitive caseins), and kappa-casein (GEM:04q211/CSN10), which prevents the precipitation of the other caseins by calcium through micelle formation in cattle (Ferretti-1990). Fujiwara-1997 demonstrated that in the human the alpha-S1, beta-, and kappa- forms of casein are closely linked and arranged in that order. By FISH, they demonstrated that the casein gene family is located on 4q21.1." |
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REF |
FUN,MEB,MAM "Ferretti L &: NAR, 18, 6829-6833, 1990 LOC,STR,GEN,EVO "Fujiwara Y &: Hum Genet, 99, 368-373, 1997 |
