Gene superfamily: cytochrome P450, subfamily II; (@CYP2ABF @CYP2C CYP2C17 @CYP2D CYP2E1 CYP2G1 CYP2J2)
SUM |
The family II is the most representative one, consisting of six subfamilies (IIA,B,C,D,E,F), which comprise a total of at least 20 genes; cytochromes of three subfamilies (A,B,E) are phenobarbital-inducible (i.e., they are phenobarbital 4-hydroxylases); CYP2C isoforms are mephenitoin 4-hydroxylases, and 2D isoforms are debrisoquin/spartein hydroxylases." |