Gene: [CYP2C/10q241] cytochrome P450, subfamily IIC in Chr 10q24.1; (CYP2C8 CYP2C9 CYP2C10 CYP2C18 CYP2C19)
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COM |
Note that the numbering of CYP2C isoforms begins not with number 1 but with number 8, since, according to the CYP gene nomenclature (see Nebert-1989 and others), numbers 1-7 are reserved for orthologous CYP2c homologues in genomes of different animal species." |
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MAP |
Gray-1995 constructed a 2.4-Mb physical map of the CYP2C gene cluster spanning approximately 500 kb on 10q24.1 and comprises 4 genes cen--RBP4(GEM:10q241/RBPI2)--CYP2C18--CYP2C19--CYP2C9--CYP2C8--qter. It seems likely that CYP2C10 (previously mapped by Inoue-1994 to this region) is a cloning artifact derived from CYP2C9." |
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REF |
MAP "Gray IC &: Genomics, 28, 328-332, 1995 LOC "Inoue K &: Jpn J Hum Genet, 39, 337-343, 1994 SUM,CLO,LOC,MOL,FAG "Meehan RR &: AJHG, 42, 26-37, 1988 FAG "Riddell DC &: CCG, 46, (HGM9), 682, 1987 CLO,SEQ,EXP,LOC "Shephard &: Ann Hum Genet, 53, 23-31, 1989 SUM,CLO,LOC,MOL,FAG "Spurr &: CCG, 46, (HGM9), 698, 1987 |
