Gene family: endogenous retroviral sequences; (ERV1 ERV3 ERVF1 ERVF2 ERVF3 ERVT1 ERVT2 ERVT3 ERVT4 ERVT5 ERVH1 ERVH2 ERVPL1 ERVPL2 ERVK1 ERVK2 ERVK3 ERVNP2 ERVSSA ERVSSAL)

SUM

The endogenous retroviral sequences (ERV) are an integral part of the human genome. Presumably, at some time during the course of human evolution, exogenous progenitors of ERVs inserted themselves into the cells of the germ line, where they have been replicated along with the host's cellular genes. Furthermore, due to their unique genomic structure, ERVs have been subjected to many amplification and transposition events, resulting in a widespread distribution of complete or partial retroviral sequences throughout the human genome. ERV sequences comprise about 1% of the human genome."

REF

COM,FAG "Bonner TI &: PNAS, 79, 4709-4713, 1982
COM,FAG "Callahan &: Science, 228, 1208-1211, 1985
COM,FAG "Callahan &: PNAS, 79, 5503-5507, 1982
REV "Lower R &: PNAS, 93, 5177-5184, 1996
COM,FAG "Mager DL, Henthorn PS: PNAS, 81, N23, 7510-7514, 1984
IDN,CLO,PRO "Martin &: PNAS, 78, 4892-4896, 1981
COM,FAG "O'Brien SJ &: Nature, 303, 74-77, 1983
COM,FAG "O'Connell C &: Virology, 138, 225-235, 1984
IDN,CLO,PRO "Rabson AB &: Nature, 306, 604-607, 1983
CLO,GEN,SEQ,EVO "Repaske R &: J Virol, 54, N3, 764-772, 1985
CLO,GEN,SEQ,EVO "Repaske R &: PNAS, 80, 678-682, 1983
IDN,CLO,PRO "Shinnick &: Nature, 293, 543-548, 1981
LOC,CYG,MOL,FAG "Steele PE &: J Virol, 59, 545-550, 1986
CLO,COD,SEQ,TRC,EXP "Steele PE &: J Virol, 56, N1, 176-182, 1985