Gene: [MHC/06p2133] major histocompatibility complex; cell-surface MHC-glycoproteins; (@MHC1 @MHC3 @MHC2)
|
GEN |
Abderrahim-1994 isolated 53 YACs with an average size of 490 kb and organized them into a single large contig covering more than 4,000 kb spanning the entire MHC region." |
|
MAF |
In the given linkage group, the gene order is as follows:
6pCen...-DP/DZ-DNA-DO-DX/DQ-DR.-CYP21A2-C4B-CYP21A1P-C4A-BF-C2-HSP70-
...-TNFA-TNFB...-HLA(B-C-X-E-A-H-G-F)- 6pTer.
The distance from BF gene (properdin factor B) to C2 = 0 cM;
from C2 to HLA-B = 2 cM;
the segment |
|
REF |
CLO,MAF "Abderrahim H &: Genomics, 23, 520-527, 1994 NOM "Bodmer JG &: Immunol Today, 11, 3-10, 1990 MAF "Campbell RD, Trowsdale J: Immunol Today, 14, 349-352, 1993 CLO,GEN,MAF "Gruen JR &: Genomics, 36, 70-85, 1996 MAF "Lawrance SK &: Science, 235, 1387-1390, 1987 MAF "Ragoussis J &: Genomics, 4, 301-308, 1989 MAF "Ragoussis J &: FEBS Lett, 204, 1-4, 1986 MAF "Trowsdale J &: Immunol Today, 12, 443-446, 1993 |
