Рис. 22 pat
Нуклеотидная и аминокислотная
последовательности липоамид дегидрoгеназы (DLD)
человека
ggaggggagaccttggc
ggacggcggagccccagcggaggtgaaagtattggcggaaaggaaaatacagcggaaaa
atg cag agc tgg agt cgt gtg tac tgc tcc ttg gcc aag aga ggc
met gln ser trp ser arg val tyr cys ser leu ala lys arg gly 15
cat ttc aat cga ata tct cat ggc cta cag gga ctt tct gca gtg
his phe asn arg ile ser his gly leu gln gly leu ser ala val 30
cct ctg aga act tac gca gat cag ccg att gat gct gat gta aca
pro leu arg thr tyr ala asp gln pro ile asp ala asp val thr 45
gtt ata ggt tct ggt cct gga gga tat gtt gct gct att aaa gct
val ile gly ser gly pro gly gly tyr val ala ala ile lys ala 60
gcc cag tta ggc ttc aag aca gtc tgc att gag aaa aat gaa aca
ala gln leu gly phe lys thr val cys ile glu lys asn glu thr 75
ctt ggt gga aca tgc ttg aat gtt ggt tgt att cct tct aag gct
leu gly gly thr cys leu asn val gly cys ile pro ser lys ala 90
tta ttg aac aac tct cat tat tac cat atg gcc cat gga aca gat
leu leu asn asn ser his tyr tyr his met ala his gly thr asp 105
ttt gca tct aga gga att gaa atg tcc gaa gtt cgc ttg aat tta
phe ala ser arg gly ile glu met ser glu val arg leu asn leu 120
gac aag atg atg gag cag aag agt act gca gta aaa gct tta aca
asp lys met met glu gln lys ser thr ala val lys ala leu thr 135
ggt gga att gcc cac tta ttc aaa cag aat aag gtt gtt cat gtc
gly gly ile ala his leu phe lys gln asn lys val val his val 150
aat gga tat gga aag ata act ggc aaa aat caa gtc act gct acg
asn gly tyr gly lys ile thr gly lys asn gln val thr ala thr 165
aaa gct gat ggc ggc act cag gtt att gat aca aag aac att ctt
lys ala asp gly gly thr gln val ile asp thr lys asn ile leu 180
ata gcc acg ggt tca gaa gtt act cct ttt cct gga atc acg ata
ile ala thr gly ser glu val thr pro phe pro gly ile thr ile 195
gat gaa gat aca ata gtg tca tct aca ggt gct tta tct tta aaa
asp glu asp thr ile val ser ser thr gly ala leu ser leu lys 210
aaa gtt cca gaa aag atg gtt gtt att ggt gca gga gta ata ggt
lys val pro glu lys met val val ile gly ala gly val ile gly 225
gta gaa ttg ggt tca gtt tgg caa aga ctt ggt gca gat gtg aca
val glu leu gly ser val trp gln arg leu gly ala asp val thr 240
gca gtt gaa ttt tta ggt cat gta ggt gga gtt gga att gat atg
ala val glu phe leu gly his val gly gly val gly ile asp met 255
gag ata tct aaa aac ttt caa cgc atc ctt caa aaa cag ggg ttt
glu ile ser lys asn phe gln arg ile leu gln lys gln gly phe 270
aaa ttt aaa ttg aat aca aag gtt act ggt gct acc aag aag tca
lys phe lys leu asn thr lys val thr gly ala thr lys lys ser 285
gat gga aaa att gat gtt tct att gaa gct gct tct ggt ggt aaa
asp gly lys ile asp val ser ile glu ala ala ser gly gly lys 300
gct gaa gtt atc act tgt gat gta ctc ttg gtt tgc att ggc cga
ala glu val ile thr cys asp val leu leu val cys ile gly arg 315
cga ccc ttt act aag aat ttg gga cta gaa gag ctg gga att gaa
arg pro phe thr lys asn leu gly leu glu glu leu gly ile glu 330
cta gat cct aga ggt aga att cca gtc aat acc aga ttt caa act
leu asp pro arg gly arg ile pro val asn thr arg phe gln thr 345
aaa att cca aat atc tat gcc att ggt gat gta gtt gct ggt cca
lys ile pro asn ile tyr ala ile gly asp val val ala gly pro 360
atg ctg gct cac aaa gca gag gat gaa ggc att atc tgt gtt gaa
met leu ala his lys ala glu asp glu gly ile ile cys val glu 375
gga atg gct ggt ggt gct gtg cac att gac tac aat tgt gtg cca
gly met ala gly gly ala val his ile asp tyr asn cys val pro 390
tca gtg att tac aca cac cct gaa gtt gct tgg gtt ggc aaa tca
ser val ile tyr thr his pro glu val ala trp val gly lys ser 405
gaa gag cag ttg aaa gaa gag ggt att gag tac aaa gtt ggg aaa
glu glu gln leu lys glu glu gly ile glu tyr lys val gly lys 420
ttc cca ttt gct gct aac agc aga gct aag aca aat gct gac aca
phe pro phe ala ala asn ser arg ala lys thr asn ala asp thr 435
gat ggc atg gtg aag atc ctt ggg cag aaa tcg aca gac aga gta
asp gly met val lys ile leu gly gln lys ser thr asp arg val 450
ctg gga gca cat att ctt gga cca ggt gct gga gaa atg gta aat
leu gly ala his ile leu gly pro gly ala gly glu met val asn 465
gaa gct gct ctt gct ttg gaa tat gga gca tcc tgt gaa gat ata
glu ala ala leu ala leu glu tyr gly ala ser cys glu asp ile 480
gct aga gtc tgt cat gca cat ccg acc tta tca gaa gct ttt aga
ala arg val cys his ala his pro thr leu ser glu ala phe arg 495
gaa gca aat ctt gct gcg tca ttt ggc aaa tca atc aac ttt tga
glu ala asn leu ala ala ser phe gly lys ser ile asn phe ter 510
attagaagattatatatttttttttctgaaatttcctgggagcttttgtagaagtcaca
ttcctgaacaggatattctcacagctccaagaatttctaggactgaattatgaaacttt
tggaaggtatttaataggtttggacaaaatggaatactcttatatctatattttacata
aatttagtattttgtttcagtgcactaatatgtaagacaaaaaggactacttattgtag
tcatcctggaatatctccgtcaactcatattttcatgctgttcatgaaagattcaatgc
ccctgaatttaaatagctcttttctctgatacagaaaagttgaattttacatggctgga
gctagaatttgatatgtgaacagttgtgtttgaagcacagtgatcaagttatttttaat
ttggttttcacattggaaacaagtcagtcattcagatatgattcaaatgtctataaacc
aaactgatgtaagtaaatggtctctcacttgttttatttaacctctaaattctttcatt
ttaggggtagcatttgtgttgaagaggttttaaagcttccattgttgtctgcaactctg
aagggtaattatatagttacccaaattaagagagtctatttacggaactcaaatacgtg
ggcattcaaatgtattacagtggggaatgaagatactgaaataaacgtcttaaatattc
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