Лечение остеоартрита: литература
Altman RD, Dean DD, Muniz OE, et al: Prophylactic treatment of canine osteoarthritis with glycosaminoglycan polysulfuric acid ester. Arthritis Rheum 32:759, 1989. An experimental study evaluating whether pretreatment with a glycosaminoglycan product can prevent formation of experimentally induced OA.
Beale BS, Goring, RL, Clemmons RM, et al: The effect of semisynthetic polysulfated glycosaminoglycan on the hemostatic mechanism in the dog. Vet Surg 19:57, 1990. A paper evaluating the effects of polysulfated glycosaminoglycan on both the intrinsic and the extrinsic hemostatic systems in healthy dogs.
Bouck GR, Miller CW, Taves CL: A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow. Vet Comp Orthop Traumatol 1:105, 1995. A prospective trial that examined ground reaction forces in dogs with clinical lameness attributable to either fragmented coronoid process or OCD lesions. Dogs were treated with either PPS or surgery. The study period was limited to 9 months.
Budsberg SC, Johnston S, Schwarz P, et al: Efficacy of etodolac for the treatment of osteoarthritis of hip joints in dogs. J Am Vet Med 214:1, 1999. A paper discussing the results of a well-controlled blinded clinical trial evaluating the efficacy of etodolac in dogs with OA in the hip.
Caron JR Fernandes JC, Martel-Pelletier J, et al: Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Arthritis Rheum 39:1535, 1996. An experimental project examining the ability of an IL-1 receptor agonist to reduce the amount of induced OA that forms in dogs.
deHann JJ, Goring RL, Beale BS: Evaluation of polysulfated glycosaminoglycan for the treatment of hip dysplasia in dogs. Vet Surg 23:177, 1994. A prospective clinical trial examining the efficacy of polysulfated gylcosaminoglycan in eliminating the clinical signs in dogs with chronic hip OA.
Ghosh P: Nonsteroidal anti-inflammatory drugs and chondroprotection: A review of the evidence. Drugs 46:834, 1993. Review of the data involving NSAIDs and cartilage metabolism.
Ghosh P, Smith M, Wells C: Second-line agents in osteoarthritis. In: Dixon JS, Furst DE, eds: Second-Line Agents in the Treatment of Rheumatic Diseases. New York: Marcel Dekker, 1993, pp 363-27. A review of the therapeutic options currently used in human medicine for the treatment of rheumatic diseases.
Hansen R: Mode of action of oral Chondroprotective agents: Round table discussion of degenerative joint disease in dogs. Canine Pract 21:9, 1996. Transcripts of an informal discussion of veterinarians, detailing their personal views on the potential uses of products claiming Chondroprotective effects.
Howell DS, Carreno MR, Pelletier JP, et al: Articular cartilage breakdown in a lapine model of osteoarthritis: Action of glycosaminoglycan polysulfate ester (GAGPS) on proteoglycan enzyme activity, hexuro-nate, and cell counts. Clin Orthop Rel Res 213:69, 1986. Experimental study evaluating the effect of a glycosaminoglycan compound's ability to modulate certain aspects of articular cartilage damage in induced OA.
Karzel K, Domenjoz R: Effects of hexosamine derivatives and uronic acid derivatives on glycosaminoglycan metabolism of fibroblast cultures. Pharmacology 5:337, 1971. In vitro study examining the effects of certain hexosamine and uronic acid derivatives on metabolism of fibroblasts.
Lust G, Williams AJ, Burton-Wurster N, et al: Effects of intramuscular injections of glycosaminoglycan polysulfates on signs of incipient hip dysplasia ingrowing dogs. Am J Vet Res 53:1836, 1992. A prospective study looking at the use of glycosaminoglycan polysulfates prophylactically on the development of OA in young growing dogs who were prone to the formation of hip dysplasia.
McNamara P, Barr S, Erb H: Hematologic, hemostatic and biochemical effects in dogs receiving an oral Chondroprotective agent for thirty days. Am J Vet Res 57:1390, 1996. A study examining the effects of Cosequin on standard hematologic, hemostatic, and platelet function test in healthy dogs.
Morrison L, Schjeide O: Absorption, distribution, metabolism, and excretion of acid mucopolysaccharides administered to animals and humans. In: Coronary Heart Disease and the Mucopolysaccharides (Glycosami-noglycans). Springfield, IL: Charles С Thomas, 1974, pp 109-127. Review of data collected on the pharmacodynamics of mucopolysaccharides in different species.
Rogachefsky RA, Dean DD, Howell DS, et al: Treatment qf canine osteoarthritis with insulin like growth factors-1 (IGF-1) ahd sodium pentosan polysulfate. Osteoarthritis Cartilage 1:105, 1993. Experimental study evaluating the effects of IGF-1 and PPS ability to modulate certain aspects of articular cartilage damage in induced OA.
Setnikar I, Giaccheti C, Zanolo G: Pharmacokinetics of glucosamine in the dog and in man. Arzneim Forschung 36:729, 1991. A review of the pharmacokinetics and pharmacodynamics of glucosamine in dogs and humans.
Setnikar I, Pacini M, Revel L: Antiarthritic effects of glucosamine sulfate studied in animal models. Arzneim Forschung 41:542, 1991. Review of data collected on the potential beneficial effects of glucosamine in different animal models.
Theiler R, Ghosh P, Brooks P: Clinical, biochemical and imaging methods of assessing osteoarthritis and clinical trials with agents claiming "chondromodulating" activity. Osteoarthritis Cartilage 2:1, 1994. A review of methods for clinically assessing the outcome efficacy of products claiming chondrocyte modification.
Todhunter RJ, Lust G: Polysulfated glycosaminoglycan in the treatment of osteoarthritis. Am J Vet Med Assoc 204:1245, 1994. An excellent review of the scientific data currently available on polysulfated glycosaminoglycan and its potential usage in the treatment of OA.
Todhunter RJ, Minor RR, Wootton JAM, et al: Effects of exercise and polysulfated glycosaminoglycan on the repair of articular cartilage defects in the equine carpus. J OrthopRes 11:782, 1993. An experimental study evaluating the effects of intra-articular polysulfated glycosaminoglycan and exercise on healing of full-thickness defects in ponies.
Verbruggen G, Veys EM: Influence of an oversulphated heparinoid upon hyaluronate metabolism of the human synovial cell in vivo. J Rheuma-tol 6:554, 1979. An experimental study evaluating the effects of oversulphated heparinoid on hyaluronate metabolism.
Yovich J, Trotter GW, Mcllwraith CW: Effects of polysulphated glycosaminoglycan on chemical and physical defects in equine articular cartilage. Am J Vet Res 48:1407, 1987. An experimental study evaluating the effects of polysulphated glycosaminoglycan on histologic healing of full and partial articular cartilage defects in horses.
