Гемопоэтический цитокинез: литература
Dale DC, Rodger Е, Cebon J, et al: Long-term treatment of canine cyclic hematopoiesis with recombinant canine stem cell factor. Blood 85:74, 1995. This study demonstrates that rc-SCF is synergistic with rcG-CSF in inducing neutrophilia and abrogating neutropenic episodes in dogs with cyclic neutropenia.
Lothrup CD, Jr, Warren DJ, Souza LM, et al: Correction of canine cyclic hematopoiesis with recombinant human granulocyte colony- stimulating factor. Blood 72:1324, 1988. This study demonstrates that the administration of rhG-CSF to canine patients, although effective in ameliorating cyclic neutropenia in affected dogs, leads to the generation of neutralizing antibodies that cross-react zeith native canine G-CSF, leading to prolonged neutropenia.
Mishu L, Callahan G, Allebban Z, et al: Effects of recombinant canine granulocyte colony-stimulating factor on white blood cell production in clinically normal and neutropenic dogs. J Am Vet Med Assoc 200:1957,1992. Ibis study demonstrates that rcG'CSF administration to normal dogs, those with cyclic neutropenia, and those undergoing autologous bone marrow transplantation, is an effective way of stimulating granulo-poiesis as well as myelopoiesis.
Nash RA, Schuening FG, Seidel K, et al: Effect of recombinant canine granulocyte-macrophage colony-stimulating factor on hematopoietic recovery after otherwise lethal total body irradiation. Blood 83:1963, 1994. This study demonstrates that although rcGM-CSF induces neutrophilia in the dog, it is not effective in promoting hematopoietic recovery when used as a single agent after lethal irradiation.
Obradovich JE, Ogilvie GK, Stadler-Morris S, et al: Effect of recombinant canine granulocyte colony-stimulating factor on peripheral blood neu-trophil counts in normal cats. J Vet Intern Med 7:65,1993. This study demonstrates that rcG-CSF is safe and effective for expanding the number of neutrophils in normal cats.
Ogilvie GK, Obradovich JE, Cooper MF, et al: Use of recombinant canine granulocyte colony-stimulating factor to decrease myelosup- pression associated with the administration of mitoxantrone in the dog. J Vet Intern Med 6:44,1992. This prospective study demonstrates that rcG-CSF reduces the duration and severity of mitoxantrone-induced myelosuppression in dogp.
deRevel T, Appelbaum FR, Storb R, et al: Effects of granulocyte colony- stimulating factor and stem cell factor, alone and in combination, on the mobilization of peripheral blood cells that engraft lethally irradiated dogs. Blood 83:3795, 1994. These studies demonstrate that both G-CSF and SCF dramatically increase the level of peripheral- blood hematopoietic progenitor and stem cells and support the view that these factors can act synergisti-cally.
Schuening FG, Storb R, Goehle S, et al: Effect of recombinant human granulocyte colony-stimulating factor on hematopoiesis of normal dogs and on hematopoietic recovery after otherwise lethal total body irradiation. Blood 74:1308, 1989. This study documents the effectiveness of rG-CSF administration in inducing full hematopoietic recovery after radiation, demonstrating (he activity of G-CSF on several hematopoietic lineages.
Walton SM: Therapeutic use of colony-stimulating factors for established neutropenic fever. W V Med J 94:26,1998.
