Незаменимые жирные кислоты в дермотерапии собак и кошек: литература

Bond R, Lloyd DH: Combined treatment with concentrated essential fatty acids and prednisolone in the management of canine atopy. Vet Rec 134:30, 1994. Demonstrates that EFA supplementation can reduce steroid requirement.

Campbell KA, Uhland CF, Dorn GP: Effects of oral sunflower oil on serum and cutaneous fatty acid concentration profiles in seborrheic dogs. Vet Dermatol 3:29, 1992. Demonstrates that sunflower oil can have effects on EFA metabolism.

Gunstone FD: Gamma linolenic acid-occurrence and physical and chemical properties. Prog Lipid Res 31:145,1992. Reviews natural sources of gamma-linolenic acid.

Harvey RG: A comparison of evening primrose oil and sunflower oil for the management of papulocrustous dermatitis in cats. Vet Rec 133:571, 1993. Demonstrates that sunflower oil is as efficacious as evening primrose oil in the management of papulocrustous dermatitis in cats.

Harvey RG: A double-blinded, prospective, placebo-controlled parailed study into the efficacy of borage and fish oil in the management of canine atopy. Vet Rec 1999.

Lawson LD, Hughes BG: Triacyl structure of plant and fungal oils containing linolenic acid. Lipids 23:313,1988. Explains why a high concentration of GLA does not necessarily mean that a given oil will have a high biologic yield.

Logas D, Kunkle GA: Double-blinded crossover study with marine oil supplementation containing high-dose eicosapentaenoic acid for the treatment of canine pruritic skin disease. Vet Dermatol 5:99, 1994. The only clinical paper, to date, that compares fish oils with an n:6 EFA source.

Miller CC, Tang W, Ziboh VA, et al: Dietary supplementation with ethyl ester concentrates of fish oil (n-3) and borage oil (n-6) polyunsaturated fatty acids induces epidermal generation of local putative anti-inflammatory metabolites. J Invest Dermatol 96:98, 1991. Demonstrates that mixtures ofn:6 and n:3 EFAs may be more efficient, in an anti-inflammatory role, than either used alone.

Miller WH, Griffin CE, Scott DW, et al: Clinical trial of DVM Derm Caps in the treatment of allergic disease in dogs: A nonblinded study. J Am Anim Hosp Assoc 25:163, 1989. One of the first publications to report that EFAs were useful in practice.

Muller GH, Kirk RW; Scott DW: Small Animal Dermatology, 4th ed. Philadephia: WB Saunders, 1989, p 725. Standard text on dermatology.

Paradis M, Lemay S, Scott DW: Efficacy of clemastine (Tavist), a fatty acid-containing product (Derm Caps), and the combination of both products in the management of canine pruritus. Vet Dermatol 2:17, 1991. Demonstrates that concurrent use of EFA and an antihistamine might have additive effects in dogs.

Paterson S: Additive benefits of EFAs in dogs with atopic dermatitis after partial response to antihistamine therapy. J Small Anim Pract 36:389, 1995. Demonstrates that concurrent use of EFAs and antihistamines might have additive effects in dogs.

Rasmussen M, Svendsen AM: Katte med alopecia. Dansk Veterinaertidsskrift 74:15,1991. Demonstrates that EFAs are useful in the management of feline dermatoses, principally pruritic ones.

Scarff DH, Lloyd DH: Double blind, placebo controlled, crossover study of evening primrose oil in the treatment of canine atopy. Vet Rec 131:97, 1992. The first publication to demonstrate that EFAs were superior to placebo in the management of atopy.

Scott DW, Miller WH, Reinhart GA, et al: Effect of an omega-3/omega-6 fatty acid containing commercial lamb and rice diet on pruritus in atopic dogs: Results of a single blinded study. Can J Vet Res 61:145,1997.

Vaughn DM, Reinhart GA, Swaim SF, et al: Evaluation of effects of dietary n-6 to n-3 fatty acid ratios on leukotriene В synthesis in dog skin and neutrophins. Vet Dermatol 5:163, 1994. Demonstrates that certain ratios of n:3 to n:6 EFAs appear to be superior to others in decreasing some components of the inflammatory response.