Рис. 2(gur). Сигнальные пути, активируемые белками НВх и PreS2 HBV
Основные сигнальные пути, активируемые белками НВх и PreS2 HBV.
РКС - protein kinase С, Pyk2 - cytosolic Ca2+-dependent proline-rich tyrosine kinase 2; Src - proto-oncogene, encoded protein is thyrosine kinase; Grb2 - growth factor receptor-bound protein 2; Ras - proto- oncogene; c-Raf-1 - cytoplasmic protein serine/threonine kinase; MEK - mitogen-activated extracellular regulated kinase 2; MAP2 - mitogen- activated protein 2; NFkB - nuclear factor кВ; IkB - inhibitor of NF-кВ; AP-1 -activator protein-1.