Gene: [00.0/FYB] FYN-binding protein (FYB-120/130; SLAP-130); [SLAP130 ]

FUN

The FYN-binding protein is involoved in T-cell receptor signaling via activation of the src protein-tyrosine kinases LCK (GEM:01p3/LCK) and FYN (GEM:06q21/FYN) (Da Silva-1993). FYB acts as a component of the FYN and SLP76 signaling cascades in T cells (Da Silva-1997b)."

REF

CLO,SEQ,EXP "da Silva AJ &: PNAS, 94, N14, 7493-7498, 1997a
EXP,FUN "da Silva AJ &: J Immunol, 158, 2007-2016, 1997b
EXP,FUN "da Silva AJ &: J Exp Med, 178, 2107-2113, 1993
CLO,SEQ,EXP "Musci MA &: JBC, 272, N18, 11674-11677, 1997

KEY

imm

CLA

coding, basic

LOC

RS

MIM

MIM: 602731

SYN

SLAP130