Gene: [01p13/CD58] antigen CD58 (LFA3; antigen CD2 ligand); lymphocyte function-associated antigen 3 (antigen CD58); [LFA3 ]

HET

The MIM Catalogue does not rule out that the antigen CD58 is identical to the protein MSK2 (an antigen identified with monoclonal antibodies T87; GEM:01q4/MSK2), and therefore MSK2 is considered in the MIM Catalogue as a secondary marker. The HGM and GEM Catalogues indicate these two genes as independent."

FAG

Antigen CD58 is a lymphocyte ligand of CD2 antigen (GEM:01p13/CD2).

EXP

Two forms of antigen CD58 that differ in membrane attachment are produced by alternative splicing."

REF

FUN,LOC "Barbosa JA &: J Immunol, 136, N8, 3085-3091, 1986
FUN,LOC "Barbosa JA &: ICSU Short Rep, 2, 107-108, 1985
REV,FUN,REL "Blann AD: Med Lab Sci, 44, 220-236, 1987
FUN,REL "Deckert &: J Immunol, 148, N3, 672-677, 1992
FUN,LOC "Sewell WA &: Immunogenetics, 28, N4, 278-282, 1988
FUN,REL "Shaw &: Nature, 323, 262-264, 1986
SEQ,PEP "Wallner BP &: J Exp Med, 166, 923-932, 1987

SWI

SWISSPROT: P19256

KEY

imm, mem

CLA

coding, basic

LOC

01 p13

MIM

MIM: 153420

SYN

LFA3

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