Gene: [01p33/HCRTR1] hypocretin (orexin) receptor 1; orexin 1 receptor (orexin-A receptor); [OX1R ]

COM

By radiation hybrid mapping, the OX1R gene was mapped between markers D1S195 and D1S443 on Chr 1p33 (Sakurai-1998)."

FUN

Orexins are mediators in the central feedback mechanism that regulates feeding behavior (Sakurai-1998)."

FAG

On the orexin 2 receptor gene see GEM:06^/HCRTR2(OX2R).

REF

CLO,SEQ,EXP,LOC,EVO "Sakurai T &: Cell, 92, N4, 573-585, 1998

KEY

neu, recp

CLA

coding, basic

LOC

01 p33

MIM

MIM: 602392

SYN

OX1R

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