Gene: [01q41/PPP2R5A] protein phosphatase 2, regulatory subunit B (B56), alpha isoform;
|
FUN |
[1] Protein phosphatase 2A (PP2A), a heterotrimeric serine/threonine
phosphatase, has been implicated in a variety of regulatory processes
including cell growth and division, muscle contraction, and gene
transcription. PP2A is a trimeric enzyme composed of a catalytic subunit,
a structural subunit, and any of several different regulatory subunits
which control its specificity.
[2] The alpha subunit gene encodes a cytoplasmic phosphoprotein." |
|
FAG |
The family of related PP2A regulatory subunits is designated the B56 family and contains at least 5 different members: GEM:01q41/PPP2R5A; GEM:11q13/PPP2R5B; GEM:03p21/PPP2R5C; GEM:06p211/PPP2R5D; GEM:07p1/PPP2R5E (McCright-1995; McCright-1996)." |
|
REF |
LOC,FAG "McCright B &: Genomics, 36, 168-170, 1996 COD,SEQ "McCright B, Virshup DM: JBC, 270, 26123-26128, 1995 |
|
KEY |
pep |
|
CLA |
coding, basic |
|
LOC |
01 q41 |
|
MIM |
MIM: 601643 |
|
EZN |
ENZYME: 3.1.3.16 |
