Gene: [02p24/DDX1] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1;

FUN

DEAD box proteins are putative RNA helicases that have a characteristic Asp-Glu-Ala-Asp (DEAD) box as 1 of 8 highly conserved sequence motifs. By altering RNA secondary structure they can influence translation initiation, splicing, and ribosome and spliceosome assembly."

FAG

The following genes coding for DEAD box polypeptides have been found: GEM:0X^/DDX3(DDX14); GEM:17q2/DDX5; GEM:11q233/DDX6; GEM:00.0/DDX7; GEM:00.0/DDX8; GEM:00.0/DDX9; GEM:11q2/DDX10; GEM:09q2/DDX10P; GEM:12p11/DDX11; GEM:12p13/DDX12."

REF

CLO "Godbout R &: PNAS, 90, 7578-7582, 1993
CLO "Schmid SR &: Mol Microbiol, 6, 283-291, 1992

KEY

nucm

CLA

coding, basic

LOC

02 p24

MIM

MIM: 601257