Gene: [12p11/DDX11] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase); keratinocyte growth factor regulated gene 2 (KRG2); [CHLR1 KRG2 ]
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COM |
The DDX11 gene is mapped to chromosome 12 by analysis of somatic cell hybrids and fluorescence in situ hybridization and is separated from DDX12 (GEM:12p13/DDX12) by 8 to 12 Mb (Amann-1996)." |
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FUN |
The DDX11 protein may be involved in cell cycle regulation (Frank-1996). |
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EXP |
DDX11 protein (as well as DDX12, see GEM:12p13/DDX12) was shown to express only in proliferating human cell lines and to be localized to the nucleolus by indirect immunofluorescence (Amann-1997)." |
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REF |
CLO,EXP,FAG "Amann J &: JBC, 272, 3823-3832, 1997 LOC,FAG "Amann J &: Genomics, 32, 260-265, 1996 CLO,EXP,FUN "Frank S, Werner S: JBC, 271, 24337-24340, 1996 |
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KEY |
nucm |
|
CLA |
coding, basic |
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LOC |
12 p11 |
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MIM |
MIM: 601150 |
|
SYN |
CHLR1 KRG2 |
