Gene: [02q1/GLC1B] glaucoma 1, open angle, B (adult-onset); [POAG ]
|
COM |
The GLC1B locus is positioned to a region of 11.2 cM that is flanked by D2S2161 and D2S176 (Stoilova-1996)." |
|
PAT |
Primary open angle glaucoma is a common ocular disorder with a characteristic degeneration of the optic nerve and visual field defects that is often associated with an elevated intraocular pressure (Stoilova-1996)." |
|
HET |
Five forms of adult-onset primary open angle glaucoma had been distinguished by linkage studies: GLC1B, mapped to chromosome 2 (GEM:02q1/GLC1B); GLC1C, mapped to chromosome 3 (GEM:03q2/GLC1C); GLC1D, mapped to 8q23 (GEM:08q23/GLC1D); GLC1E, mapped to 10p15-p14 (GEM:10p1/GLC1E); and GLC1F, not mapped yet (GEM:00.0/GLC1F)." |
|
REF |
LOC,LIN,PAT "Stoilova D &: Genomics, 36, 142-150, 1996 |
|
KEY |
eye |
|
CLA |
unknown, basic |
|
LOC |
02 q11-13 |
|
MIM |
MIM: 137760 |
|
SYN |
POAG |
