Gene: [02q23/GCG] glucagon; hyperproglucagonemia (glucagon);
HIS | MIM-88 included three glucagon markers: two glucagon types (normal and high molecular ones) and a hyperproduction of the high molecular type. They were described under the numbers 13803, 13805, and 14527, respectively. In the MIM-90, one of the markers (13805) was exluded, and hyperproglucagonemia is considered as a secondary marker that depends on glucagon." |
FAG | [1] Glucagon receptor is mapped to Chr 17 (GEM:17q25/GCGR). [2] Glucagon-like peptide 1 (GLP1) is a hormone derived from the preproglucagon molecule and is secreted by intestinal L cells. GLP1 receptor is mapped to Chr 6 (GEM:06p21/GLP1R)." |
REF | GEN,SEQ "Bell GI &:
Nature, 304, (28 Jul), 368-371, 1983 LOC,PRO "Lu-Kuo J &: Genomics, 16, 173-179, 1993 LOC,PRO "Schroeder WT &: CCG, 38, 76-79, 1984 LOC,PRO "Tricoli JV &: CCG, 37, 598, 1984a LOC,PRO "Tricoli JV &: Diabetes, 33, 200-202, 1984b GEN,SEQ "White JW, Saunders GF: NAR, 14, 4719-4730, 1986 |
SWI | SWISSPROT: P01275 |
KEY | horm, carb |
CLA | coding, basic |
LOC | 02 q23 |
MIM | MIM: 138030 |
