Gene: [02q3/PTPRN] protein tyrosine phosphatase, receptor type, N; islet cell antigen 512 (IA-2); islet cell autoantigen 3 (ICA512);
COM | van den Maagdenberg-1996 used fluorescence in situ hybridization to localize PTPRN to human Chr 2q35-q36.1." |
FUN | [1]Systematic name:
protein-tyrosine-phosphate phosphohydrolase. [2] Reaction catalyzed: protein tyrosine phosphate + H(2)O = protein tyrosine + orthophosphate." |
FAG | This gene is homologous to another receptor-type PTP, IA-2-beta (GEM:07q36/PTPRN2), that is expressed in brain and pancreas and was also found to be an autoantigen in IDDM." |
REF | IDN,COD,SEQ,EXP,FAG "Lan MS &: DNA Cell Biol, 13, 505-514,
1994 COD,EXP,MOP "Rabin DU &: J Immunol, 152, 3183-3188, 1994 CLO,SEQ "Solimena M &: EMBO J, 15, 2102-2114, 1996 COD,LOC,FAG "van den Maagdenberg AMJM &: CCG, 73, 145-148, 1996 |
SWI | SWISSPROT: Q16849 |
KEY | pep, recp |
CLA | coding, basic |
LOC | 02 q35-36.1 |
MIM | MIM: 601773 |
EZN | ENZYME: 3.1.3.48 |
