Gene: [03p/ITIH4] inter-alpha (globulin) inhibitor, H polypeptide-like 1; inter-alpha (globulin) inhibitor H4; inter-alpha-trypsin inhibitor, heavy chain-related protein; plasma kallikrein-sensitive glycoprotein; [IHRP PK120 ]

COM

The ITIH4 gene was mapped to 3p21.2-p14.1 by FISH (Jean-1997).

EAG

In both human and mouse, the ITIH4 gene maps near the ITIH1 (GEM:03p21/ITIH1) and ITIH3 (GEM:03p21/ITIH3) genes."

FUN

The ITIH4 glycoprotein circulates in the plasma at a concentration of 80 micrograms per milliliter and is cleaved by KLK3 (GEM:04q35/KLK3) into smaller fragments (Nishimura-1995)."

REF

LOC,FAG,EAG,HUM,MOU "Jean L &: Genomics, 41, N1, 139-140, 1997
COD,SEQ,EXP "Nishimura H &: FEBS Lett, 357, N2, 207-211, 1995
COD,SEQ,EVO "Saguchi K &: J Biochem, 117, N1, 14-18, 1995
CLO,SEQ,LOC "Tobe T &: CCG, 71, 296-298, 1995

SWI

SWISSPROT: Q14624

KEY

pep

CLA

coding, basic

LOC

03 p21.2-14.1

MIM

MIM: 600564

SYN

IHRP PK120