Gene: [04q35/F11] coagulation factor XI (plasma thromboplastin antecedent); hypothromboplastinemia (Rosenthal syndrome, coagulation factor XI deficiency);
HIS | Preliminary data (Futterweit-1986) about the localization of F11 in chromosome 15q (on the basis of one case of plasma thromboplastin deficiency in a patient with Prader-Willi chromosomal syndrome; see GEM:15q1/PWCR) were not confirmed." |
GEN | The gene length is 23 kb. Exons: 15; introns: 14. |
REF | PAT,PHE,FOG "Aghai &:
Scand J Haematol, 32, 327-331, 1984 PRO,GEN,MOP "Asakai R &: Biochemistry, 26, 7221-7228, 1987 PAT,PHE,FOG "Bertina, Veltkamp: Brit J Haematol, 42, 623-635, 1979 PAT,PHE,FOG "Braunstein &: J Clin Invest, 68, 1420-1426, 1981 PEP,SEQ,MOP "Fujikawa K &: Biochemistry, 25, 2417-2424, 1986 HIS,PAT "Futterweit &: JAMA, 255, 3280-3282, 1986 LOC "Kato A &: CCG, 52, 77-78, 1989 PAT,PHE,FOG "Litz &: Am J Hematol, 28, 8-12, 1988 PAT,PHE,FOG "Mannhalter &: Blood, 70, 31-37, 1987 PAT,PHE,FOG "Ragni &: Blood, 65, 719-724, 1985 PAT,PHE,FOG "Rapaport &: Blood, 18, 149-165, 1961 PAT,PHE,FOG "Rimon &: Blood, 48, 165-174, 1976 HIS,PAT,PHE,FOG "Rosenthal &: Blood, 10, 120-131, 1955 HIS,PAT,PHE,FOG "Rosenthal &: Proc Soc Exp Biol Med, 82, 171-174, 1953 |
SWI | SWISSPROT: P03951 |
KEY | hem, clot |
CLA | coding, basic |
LOC | 04 q35 |
MIM | MIM: 264900 |
EZN | ENZYME: 3.4.21.27 |
