Gene: [05q1/CTLA3] cytotoxic T-lymphocyte-associated serine esterase 3; granzyme A (Hanukah factor serine protease); T cell/natural killer cells serine esterase 3;
FAG | See GEM:14q112/CTLA1. |
FUN | [1] Hydrolysis of
proteins, including fibronectin, type IV collagen and nucleolin. [2] Preferential cleavage: arg-|-xaa, lys-|-xaa >> phe-|-xaa in small molecule substrates." |
REF | PRO,SEQ,MOP,LOC "Gershenfeld HK &: PNAS, 85, N4,
1184-1188, 1988 SEQ,PRO,EXP "Gershenfeld HK &: Science, 232, 854-858, 1986 |
SWI | SWISSPROT: P12544 |
KEY | imm, pep |
CLA | coding, basic |
LOC | 05 q11-12 |
MIM | MIM: 140050 |
EZN | ENZYME: 3.4.21.78 |
