Gene: [06q2/PLG] plasminogen (fibrinase; fibrinolysin precursor);

EVO

The amino acid sequence of this protein is shown to be highly homologous to that of apolipoprotein(a), the gene for the latter (see GEM:06q27/APOLPA) being closely linked to the PLG gene. APOLPA is involved in the pathogenesis of the atherosclerosis and coronary disease."

LIK

GEM:02^/PLGL.

PSG

GEM:00.0/PLGP1; GEM:00.0/PLGP2.

REF

PEP,SEQ,EVO "Eaton &: PNAS, 84, N10, 3224-3228, 1987
SEQ,EXP "Forsgren M &: FEBS Lett, 213, 254-260, 1987
LOC,LIN,POL "Murray JC &: AJHG, 40, 338-350, 1987
PRO,LOC "Swisshelm &: CCG, 40, (HGM8), 756, 1985
REV,FUN,EXP,MEB "Wun T-C: CRC Crit Rev Biotech, 8, N2, 131-148, 1988

SWI

 SWISSPROT: P00747

KEY

hem, clot, pep

CLA

coding, basic

LOC

06 q26-27

MIM

 MIM: 173350

EZN

 ENZYME: 3.4.21.7

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