Gene: [06q2/PRKCSL] protein kinase C substrate 80K-L (myristoylated alanine-rich, MARCKS); [MACS PKCSL ]

COM

Rao-1994 assigned the MACS gene to Chr 6q22.2. Stumpo-1998 mapped this gene to Chr 6p21."

FUN

The myristoylated, alanine-rich protein MARCKS, is a widely expressed, prominent substrate for protein kinase C (see FAM:PRKC/00.0) which is a key enzyme of intracellular signal transduction."

FAG

About the gene coding for MARCKS-like protein (MacMarcks) see in GEM:01p34/MLP."

REL

GEM:19p132/PRKCSH; GEM:21^/PRKCSLL1.

REF

LOC "Boyle &: CCG, 58, (HGM11), 1908, 1991
PRO,COD,SEQ,EXP "Harlan DM &: JBC, 266, 14399-14405, 1991
MEB "Hirai M, Shimizu N: Biochem J, 270, 583-589, 1990
LOC "Rao PH &: CCG, 66, N4, 272-273, 1994
LOC "Sakai K &: CCG, 58, (HGM11), 1916, 1991
CLO,SEQ,EXP,LOC "Stumpo DJ &: Genomics, 49, N2, 253-264, 1998
LOC "Volz A &: Genomics, 21, 464-472, 1994

SWI

SWISSPROT: P29966

KEY

sign

CLA

coding, basic

LOC

06 q21-22.2

MIM

MIM: 177061

SYN

MACS PKCSL