Gene: [07q/MDH2] malate dehydrogenase, NAD (mitochondrial);

COM

EN-IUB indicates, under the common name 'malate dehydrogenase', four enzymes that differ in (1) mode of malate oxidation (with or without decarboxylation), (2) range of substrate specificity, and (3) the nature of the proton acceptor used (NAD+ or NADP+); see EC:1.1.1.37, EC:1.1.1.38, EC:1.1.1.39, and EC:1.1.1.40."

FUN

Systematic name: (S)-malate:NAD+ oxidoreductase. The reaction catalyzed: (S)-malate + NAD+ = oxaloacetate + NADH."

REL

See GEM:02p23/MDH1.

REF

LOC,CYG "Shimizu &: CCG, 37, (HGM7), 581-582, 1984
LOC,CYG "Van Heyningen V &: Ann Hum Genet, 38, 295-303, 1975

SWI

SWISSPROT: P40926

KEY

mito, cytr

CLA

coding, basic

LOC

07 q11-q22

MIM

MIM: 154100

EZN

ENZYME: 1.1.1.37

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