Gene: [08p2/ATP6B2] ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 56/58kD, isoform 2 (brain); vacuolar proton pump 3 (58kD subunit), isoform 2 (brain);

FUN

Systematic name: ATP phosphohydrolase (H+ -transporting, acyl-phosphate linked). The reaction catalyzed: ATP + H(2)O = ADP + orthophosphate."

REF

CLO,SEQ "Bernasconi P &: JBC, 265, 17428-17431, 1990
CLO,SEQ "Nelson RD &: PNAS, 89, 3541-3545, 1992
LOC "Schuler GD &: Science, 274, 540-546, 1996

SWI

 SWISSPROT: P21281

KEY

neu, mem, ion, lys

CLA

coding, basic

LOC

08 p22-21

MIM

 MIM: 192132

EZN

 ENZYME: 3.6.1.34