Gene: [11q11/OSBP] oxysterol binding protein;
|
FUN |
The product of the OSBP gene is an intracellular protein participating in steroid transport from lysosomes to the nucleus where steroid compounds suppress the expression of genes of LDL receptor (GEM:19p132/LDLR) and some enzymes (GEM:05q1/HMGCR; GEM:05p1/HMGCS1; GEM:01p1/HMGCS2)." |
|
REF |
CLO,COD,EXP,LOC,EAG "Hsieh &: AJHG, 45, A143, 1989 CLO,COD,SEQ,EXP,LOC,EAG "Levanon D &: Genomics, 7, N1, 65-74, 1990 |
|
KEY |
lip, trp, ster |
|
CLA |
coding, basic |
|
LOC |
11 q11 |
|
MIM |
MIM: 167040 |
