Gene: [11q22/API1] apoptosis inhibitor 1; inhibitor of apoptosis 2; [cIAP1 HIAP2 ]
COM | Rajcan-Separovic-1997 used fluorescence in situ hybridization to map API1/HIAP2 to the boundary of 11q22 and 11q23. This is the same locus as the API2 gene, and the authors speculate that these genes arose by tandem duplication." |
FAG | API genes (GEM:11q22/API2; GEM:0Xq25/API3; GEM:00.0/API4) are members of a human multigene family that shows extensive homology to baculovirus IAPs (inhibitor of apoptosis proteins) and that encodes proteins showing significant inhibition of apoptosis." |
REF | CLO,LOC,FAG "Liston P &: Genomics, 46, 495-503,
1997 CLO,SEQ "Liston P &: Nature, 379, 349-353, 1996 PRO,LOC,FAG "Rajcan-Separovic E &: Genomics, 37, 404-406, 1996 CLO,SEQ "Rothe M &: Cell, 83, 1243-1252, 1995 CLO,SEQ "Uren AG &: PNAS, 93, 4974-4978, 1996 |
SWI | SWISSPROT: Q13490 |
KEY | ont |
CLA | coding, basic |
LOC | 11 q22 |
MIM | MIM: 601712 |
SYN | cIAP1 HIAP2 |
