Gene: [12q13/GLI1] chromatin-associated GLI-phosphoprotein 1 (oncogene GLI); zinc finger oncoprotein GLI1; oncogene GLI (glioma-associated oncogene homolog); GLI-Kruppel family member GLI1 (oncogene GLI); glioblastoma multiform (astrocytoma; liability?); [GLI ]
IDN | GLI oncogene was identified by the 50-fold amplification and enhanced expression in malignant glioma cells (MIM:137800) and daughter cell strains (Kinzler-1987,1998)." |
FAG | On other GLI-Kruppel genes, see GEM:19^/HKR1. |
PRO | The probe pKK36P1 contains a 1.55-kb PstI fragment of gDNA cloned in the plasmid pGEM3." |
REF | LOC,MOL,PRO "Arheden K &: Hum Genet, 82, N1, 1-2,
1989 HIS,PAT,PHE,FOG "Armstrong, Hanson: Neurology, 19, 1061-1063, 1969 CYG,PAT "Bigner &: Cancer Res, 88, 405-411, 1988 HIS,PAT,PHE,FOG "Chemke &: Am J Med Genet, 21, 731-735, 1985 LOC,MOL,PRO "Dal Cin &: CCG, 51, (HGM10), 982-983, 1989 HIS,PAT,PHE,FOG "de Tribolet &: Neurochirurgia, 22, 225-228, 1979 HIS,PAT,PHE,FOG "Heuch, Blom: J Neurol, 233, 142-144, 1986 HIS,PAT,PHE,FOG "Isamat &: J Neurosurg, 41, 573-575, 1974 HIS,PAT,PHE,FOG "King, Eisinger: Guthrie Clin Bull, 35, 169-175, 1966 GEN,PRO,EXP,EVO "Kinzler KW &: Nature, 332, 371-374, 1988 GEN,PRO,EXP,EVO "Kinzler KW &: Science, 236, 70-73, 1987 HIS,PAT,PHE,FOG "Kjellin &: J Neuropath Exp Neurol, 19, 528-537, 1960 HIS,PAT,PHE,FOG "Koch, Waldbaur: Z Allg Med, 57, 1219-1224, 1981 HIS,PAT,PHE,FOG "Leblanc &: Neurosurgery, 18, 480-482, 1986 HIS,PAT,PHE,FOG "Parkinson, Hall: J Neurosurg, 19, 424-426, 1962 HIS,PAT,PHE,FOG "Reese &: Sth Med J, 37, 424-428, 1944 HIS,PAT,PHE,FOG "Schianchi &: Acta Neuropathol, 52, 153-155, 1980 HIS,PAT,PHE,FOG "Vieregge &: J Neurol, 234, 220-232, 1987 HIS,PAT,PHE,FOG "Von Motz &: Neurology, 27, 1038-1041, 1977 |
SWI | SWISSPROT: P08151 |
KEY | onc, neu |
CLA | coding, basic |
LOC | 12 q13.2-.3 |
MIM | MIM: 165220 |
SYN | GLI |
