Gene: [12q22/NEDD1] neural precursor cell expressed, developmentally down-regulated 1;
|
COM |
Takai-1995 assigned the NEDD1 gene to Chr 12q22 by fluorescence in situ hybridization." |
|
FAG |
[1] NEDD genes were so named by Kumar-1992 for 'neural precursor cell
expressed developmentally and down-regulated'. NEDD genes are expressed
strongly during the early development of the central nervous system
but at much reduced levels in adult tissues. The expression and biologic
activity of NEDDs suggests a potential role as a tumor suppressor genes.
[2] On other NEDDs see GEM:07q35/CASP2(=NEDD2); GEM:00.0/NEDD3; GEM:15q/NEDD4; GEM:02q37/NEDD5; GEM:00.0/NEDD6; GEM:00.0/NEDD7; GEM:00.0/NEDD8; GEM:00.0/NEDD9; GEM:00.0/NEDD10." |
|
REF |
IDN,MOU,NOM "Kumar S &: BBRC, 185, N3, 1155-1161, 1992 LOC "Takai S &: Hum Genet, 95, 96-98, 1995 |
|
KEY |
neu, ont |
|
CLA |
coding, basic |
|
LOC |
12 q22 |
|
MIM |
MIM: 600372 |
