Gene: [12q242/NOS1] nitric oxide synthase 1 (neuronal);
FUN | The nitric oxide is suggested to be a physiologic mediator of erectile function in rat (Burnett-1992). NOS may be responsible for the synthesis of nitric oxide during penile erection and may be involved in control of the tone of the urethra, prostate, and bladder (Magee-1996). The exact function of human NOS2A is unknown." |
REL | GEM:17q1/NOS2A; GEM:17^/NOS2B; GEM:17^/NOS2C; GEM:07q36/NOS3. |
REF | CLO,EXP "Bredt DS &:
Nature, 351, 714-718, 1991 RAT,FUN "Burnett AL &: Science, 257, 401-403, 1992 CLO,LOC "Kishimoto J &: Genomics, 14, 802-804, 1992 RAT,FUN,EXP "Magee T &: BBRC, 226, 145-151, 1996 CLO,LOC "Marsden PA &: JBC, 268, 17478-17488, 1993 SEQ,EXP,GEN "Xie J &: PNAS, 92, 1242-1246, 1995 CLO,LOC "Xu W &: CCG, 64, 62-63, 1993 |
SWI | SWISSPROT: P29475 |
KEY | neu |
CLA | coding, basic |
LOC | 12 q24.2 |
MIM | MIM: 163731 |
EZN | ENZYME: 1.14.13.39 |
