Gene: [16q24/HSD17B2] hydroxysteroid (17-beta) dehydrogenase 2 (microsomal); estradiol 17 beta-dehydrogenase 2;

FUN

[1] Systematic name: 11-beta-hydroxysteroid:NADP+ 11-oxidoreductase.
[2] Catalysed reaction: 11-beta-hydroxysteroid + NADP(+) = 11-oxosteroid + NADPH.
[3] HSD17B2 has also 20 alpha-hydroxysteroid dehydrogenase activity."

REL

GEM:17q/HSD17B1.

SWI

SWISSPROT: P37059

KEY

horm, sex, mtbd, mem

CLA

coding, basic

LOC

16 q24.1-.2

MIM

MIM: 109685

EZN

ENZYME: 1.1.1.62

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