Gene: [17q/HSD17B1] hydroxysteroid (17-beta) dehydrogenase 1 (placental); estradiol 17 beta-dehydrogenase 1;
FUN | [1]
Systematic name: 11-beta-hydroxysteroid:NADP+ 11-oxidoreductase. [2] Catalysed reaction: 11-beta-hydroxysteroid + NADP(+) = 11-oxosteroid + NADPH. [3] HSD17B1 has also 20 alpha-hydroxysteroid dehydrogenase activity." |
REL | GEM:16q24/HSD17B2; GEM:09q22/HSD17B3; GEM:05q2/HSD17B4; GEM:17q/HSD17BP1." |
REF | PRO,LOC "Berube &:
CCG, 51, (HGM10), 962, 1989 LOC,POL "Winqvist R &: Hum Genet, 85, 473-476, 1990 |
SWI | SWISSPROT: P14061 |
KEY | horm, sex, mtbd |
CLA | coding, basic |
LOC | 17 q12-21 |
MIM | MIM: 109684 |
EZN | ENZYME: 1.1.1.62 |
