Gene: [17p133/C1QBP] complement component 1, q subcomponent binding protein; hyaluronan-binding protein 1; splicing factor, arginine/serine-rich 1 associated protein (p32); [HABP1 GC1Q-R ]

HIS

Initially the HABP1 was found as a protein (from HeLa cells) that was copurified with the pre-mRNA splicing factor SF2 (GEM:17q2/SFRS1) (Krainer-1991)."

MOP

The predicted 34-kD protein is highly acidic (estimated pI of 4.04) and contains a hyaluronic acid-binding domain as found in hyaladherin (GEM:11p13/CD44). The protein contains a potential tyrosine sulfation site, 3 predicted N-linked glycosylation sites, and at least 1 potential phosphorylation site for kinases. The recombinant protein, expressed in E. coli, was shown to bind hyaluronic acid-Sepharose (Deb-1996)."

FAG

Another gene coding for hyaluronan-binding protein has been found: GEM:10q2/HABP2."

REF

COD,SEQ,MEB,EXP "Deb TB, Datta K: JBC, 271, 2206-2212, 1996
CLO,EXP "Ghebrehiwet B &: J Exp Med, 179, N6, 1809-1821, 1994
LOC "Guo N &: CCG, 77, N3-4, 283-284, 1997
COD,SEQ,EXP "Honore B &: Gene, 134, 283-287, 1993
IDN,EXP "Krainer AR &: Cell, 66, 383-394, 1991
LOC "Majumdar M, Datta K: Genomics, 51, N3, 476-477, 1998

SWI

SWISSPROT: Q07021

KEY

imm, comp

CLA

coding, basic

LOC

17 p13.3

MIM

MIM: 601269

SYN

HABP1 GC1Q-R

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