Gene: [11p13/CD44] antigen CD44 (gp90; lymphocyte homing/adhesion receptor; lethal antigen 3); antigen MDU2 (MDU3; monoclonal antibodies A1G3, A3D8); antigen MIC4 (monoclonal antibodies F10.44.2, mab4); Lutheran blood group inhibitor? (MIM:111150; INLU; antigen CD44); [MFI1 S3 MIC4 ]
COM |
Antigens MIC4 and MDU3 are described in the MIM Catalogue under the numbers 143040 and 158060?. They were determined to be identical to the product of gene CD44." |
FUN |
The CD44 peptide possibly inhibits the expression of the Lutheran blood group antigen on the surface of red blood cells." |
EXP |
Hematopoietic and epithelial forms of antigene CD44 are produced by alternative splicing." |
REF |
FUN,LOC,CYG,LIN "Ala-Kapee &: CCG, 51, (HGM10), 948-949, 1989 LOC,CYG "Forsberg UH &: Eur J Immunol, 19, 409-412, 1989a LOC,CYG "Forsberg UH &: Immunogenetics, 29, 405-407, 1989b LOC,CYG "Francke U &: Somat Cell Genet, 9, 333-334, 1983 LOC,LIN,MOL,MAP "Glaser &: CCG, 46, (HGM9), 620-621, 1987 LOC,CYG "Goodfellow &: Eur J Immunol, 8, 659-663, 1982 MOU,CLO,COD "Lasky &: Cell, 56, 1045-1055, 1989 PEP,MEB "Omary &: Immunogenetics, 27, 460-464, 1988 IDN,FUN,MEB "Stefanova &: Immunogenetics, 29, 402-404, 1989 LOC,CYG "Van Heyningen &: CCG, 40, (HGM8), 768, 1985 |
KEY |
mem, hem, imm |
CLA |
coding, basic |
LOC |
11 p13 |
MIM |
MIM: 107269 |
SYN |
MFI1 S3 MIC4 |
Ссылки:
- Gene: [11q1/MDU1] antigen MDU1, heavy subunit (p40, monoclonal antibodies 4F2, 44D7); sodium-calcium exchanger (NACAE); [M4F2 MGP4F2 ]
- Gene: [17p133/C1QBP] complement component 1, q subcomponent binding protein; hyaluronan-binding protein 1; splicing factor, arginine/serine-rich 1 associated protein (p32); [HABP1 GC1Q-R ]
- Gene: [19q132/LU] Lutheran blood group; B-cell adhesion molecule (BCAM); Auberger B antigen; antigen MSK19 (gp95; monoclonal antibody F8); [BCAM MSK19 ]
- Gene: [02q3/GPC1] glypican 1;
- Gene: [04q2/SPP1] secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); [OPN BNSP ]