Gene: [17q1/CSF3] colony stimulating factor 3 (granulocyte); granulocyte growth factor 3 (colony-stimulating); pluripoietin; [GCSF]

COM

Localization in 17q21-22, determined by Kanda-1987 and Tweardy-1987, was later refined by Xu-1988."

LIN

According to Xu-1988,1989, CSF3 gene and the gene for TH alpha receptor (GEM:17q1/THRA) are physically mapped, being located no more than 270 kb apart, since the gene-specific DNA probes reveal common 270 kb fragments in NotI/MluI, NotI/NruI, and MluI/NaeI double chr 17 DNA endohydrolysates."

FAG

The gene for granulocyte growth factor receptor is mapped to the short arm of chr 1; see GEM:01p3/CSF3R."

REF

GEN,SEQ,EXP,PAT "Cheng &: Blood, 71, N1, 204-208, 1988
LOC,MOL "Kanda N &: Somat Cell Mol Genet, 13, N6, 679-684, 1987
LOC,MOL "Le Beau MM &: Leukemia, 1, N12, 795-799, 1987
PRO,SEQ,EXP "Nagata S &: EMBO J, 5, N3, 575-581, 1986a
PRO,SEQ,EXP "Nagata S &: Nature, 319, 415-418, 1986b
LOC,MOL "Simmers RN &: Hum Genet, 78, 134-136, 1988
LOC,MOL "Simmers RN &: Blood, 70, 330-332, 1987
PRO,SEQ,LOC "Tweardy DJ &: Oncogene Res, 1, 209-220, 1987
LIN,MOL,MAG,MAF "Xu WM &: CCG, 51, (HGM10), 1111-1112, 1989
LIN,MOL,MAG,MAF "Xu WM &: PNAS, 85, N22, 8563-8567, 1988

SWI

SWISSPROT: P09919

KEY

cyk, onc

CLA

coding, basic

LOC

17 q11.2-12

MIM

MIM: 138970

SYN

GCSF

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