Gene: [17q25/ACTG1] actin, gamma 1, cytoplasmic; [ACTG ]

FAG

Several processed gamma-actin pseudogenes are found. Two of them mapped to Chrs 3 and Y and sequenced by Gomez-Pedrozo,1987, differ from gamma pseudogene described by Leube,1986 and registered under GEM:00.0/ACTGP3. Emi,1988 described the fourth gamma pseudogene, which overlaps with the coding region of salivary amylase gene AMY1 in Chr 1p21 (GEM:01p21/ACTGP4). Four additional actin-like sequences are also found (GEM:0Xp112/ACTL1, GEM:02^/ACTL3, GEM:03^/ACTL4, and GEM:21q/ACTL5) that are not yet assigned to a certain type (ACTL2 is now identified as the second gamma-actin pseudogene 2 mapped to Chr Yq11; GEM:0Yq11/ACTGP2). As for other four ACTL, it remains unclear, which of them actually differ from already mapped beta and gamma pseudogenes, or represent alpha pseudogenes; see FAM:ACT/00.0."

PSG

GEM:03^/ACTGP1, GEM:0Yq11/ACTGP2, GEM:00.0/ACTGP3, GEM:01p21/ACTGP4, GEM:01p21/ACTGP5, GEM:01p21/ACTGP6, GEM:01p21/ACTGP7, GEM:01p21/ACTGP8, GEM:00.0/ACTGP9."

GEN

The gene length is 3.5 kb; the length of cDNA is 1.9 kb.

REF

GEN,SEQ,MAF "Emi M &: Gene, 62, 229-235, 1988
LOC,GEN,FAG,EXP "Erba HP &: Mol Cell Biol, 8, N4, 1775-1789, 1988
PRO,SEQ,EVO "Erba HP &: NAR, 14, N13, 5275-5294, 1986
GEN,SEQ,LOC "Gomez-Pedrozo &: J Hum Evol, 16, 215-230, 1987
GEN,SEQ "Leube R, Gallwitz: NAR, 14, 6339, 1986
FAG "Ponte P &: Mol Cell Biol, 3, 1783-1791, 1983
POL,MOL,PRO "Singh &: CCG, 51, (HGM10), 1080-1081, 1989
LOC "Ueyama H &: CCG, 74, 221-224, 1996

KEY

cysk

CLA

coding, basic

LOC

17 q25

MIM

MIM: 102560

SYN

ACTG

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