Gene: [19q13/BAX] BCL2-associated X protein (apoptosis derepressor);

FUN

BAX accelerates programmed cell death by binding to the apoptosis repressor BCL-2 (see GEM:18q2133/BCL2)."

EXP

A 21kD membrane protein alpha and the three cytoplasmic proteins 24kD beta, 4kD gamma, and 15kD delta are produced by alternative splicing."

REF

LOC "Apte SS &: Genomics, 26, 592-594, 1995
SEQ "Oltvai ZN &: Cell, 74, 609-619, 1993

KEY

mem

CLA

coding, basic

LOC

19 q13.3-.4

MIM

MIM: 600040

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